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New-onset constipation in patients over age 50 or accompanied by iron-deficiency anemia warrants evaluation to rule out colorectal pathology, per gastroenterology guidelines

[DOI] [PubMed] [Google Scholar] 457.Ridker, P

Similarly, cystine depletion using cyst(e)inase reproduced significant tumor suppression in the KPC model (138)

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It tells us something critical about how dose level influences digestive outcomes
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