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(28) The crude incidence rates of LLA were 6.1 per 10,000 person-years for GLP-1 receptor agonists, 1.5 for SGLT-2 inhibitors, 4.6 for DPP-4 inhibitors, and 1.9 for older agents

Dosing regimens are constructed around these characteristics, simplifying adherence

In semaglutides extension, about two-thirds returned within one year

Taking zinc on the same day as semaglutide injections or with meals can further reduce absorption due to competitive binding in the digestive tract

Chronic GLP1RA therapy also reduces glomerular hyperfiltration, oxidative stress and profibrotic signalling in the kidney

Ozempic is only available on prescription and there are no generic versions of Ozempic registered in South Africa