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A recent propensity-matched cohort study also identified obesity as a risk factor for corticosteroid use, therapy escalation, and colectomy in UC patients (85)

(2019, February 26)
Optimizing GLP1 hormone production through the lens of the gut microbiome

From a regulatory perspective, this observation mirrors electronic practices such as deleting chromatograms, overwriting results, or failing to retain audit trails

On side effects, both classes most commonly produce gastrointestinal symptoms - nausea, vomiting, diarrhea, and constipation - primarily during dose escalation

Key advances In the SURMOUNT-1 trial for obesity, adults with overweight or obesity without type 2 diabetes mellitus achieved placebo-subtracted weight loss of up to 20% after 72 weeks of the GLP1GIP receptor co-agonist tirzepatide, with a similar safety profile to high-dose semaglutide 5
