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Alongside their respective treatment arms, patients received individualized counseling at every visit to encourage a healthy diet and a goal of 60 minutes per day of moderate-to-high-intensity physical activity. Figure 2

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Therefore, careful consideration and possibly an alternative route of administration could be necessary when administering time or narrowtherapeuticindexdependent medications together with tirzepatide

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Tirzepatide is important in metabolic research because it gives researchers a dual-incretin model for studying how GIP and GLP-1 pathways interact within glucose response, satiety signaling, and energy-balance systems