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Our findings support the use of semaglutide as a first-line GLP-1RA for patients with obesity and T2DM, particularly when reduction in visceral fat and cardiovascular risk is prioritized

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R., Sesti, G., Mannucci, E., Courrges, J

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Wegovy (semaglutide) is a single-pathway medicine in this context

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This single alteration provides substantial resistance to enzymatic degradation, extending the peptide's utility in metabolic research

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