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Although not as spectacular as the impact of COVID-19 on the health of society, diabetes is sure and steady in its burden, increasing in prevalence and with an increase in mortality and morbidity over time

Finally, beware of compounded GLP-1 drugs, which became popular during a GLP-1 drug shortage starting in 2022

Dose reduction of concomitant medications is typically required when initiating GLP-1 or dual-agonist therapy

You should also ask whether the program addresses muscle preservation

You should consult a healthcare provider if you are unsure about your current dose escalation step, experiencing persistent side effects, transitioning between different semaglutide products, combining semaglutide with other peptide stacks , or have underlying conditions that might affect how you metabolize the medication

Clinical trials show that most people regain weight after stopping GLP-1 medications, with approximately two-thirds of lost weight returning within a year