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Due to a short plasma half-life of native GLP-1, several synthesized GLP-1 receptor agonists (RAs) were developed for type 2 diabetes mellitus (DM) treatment
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Plasma ANP increased after liraglutide in both groups, most in patients with eGFR<30 ml/min/1.73 m2 group
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Adipokines (e.g., leptin and adiponectin) are regulated by DPP-4 and may influence bone remodeling and energy metabolism in a paracrine manner
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