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10.2337/ds16-0061 [EL 2

Here, we present a ligand-based proximity labeling approach to interrogate the native cell membrane interactome for the GLP-1 receptor after agonist simulation

Damage to specific hypothalamic nuclei leads to hyperphagia, central insulin and leptin resistance, decreased sympathetic activity, reduced energy expenditure, and rapid weight gain

In contrast, DPP-4 expressed within murine hepatocytes, adipocytes, or gut enterocytes is not required for physiological regulation of glucose tolerance and is dispensable for the glucoregulatory actions of DPP4i (20, 2325)

A deeper understanding of IR can be achieved with a more systematic approach involving large-scale omics to study the molecular landscape is of major importance in addition to exploring new intervention strategies to prevent abnormal IR syndrome

Table 2 CSF, cerebrospinal fluid