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However, although the FcRn recycling is proposed as a half-life extension mechanism for albumin-bound peptides in general, to the best of our knowledge there is no existing experimental evidence that proves FcRn recycling occurs for acylated GLP-1 RAs
But Novo Nordisk's CEO Doustdar has argued that those dietary requirements won't hinder uptake

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One size does not fit all: Understanding microdosing semaglutide for diabetes in multidose pens

Experts even say that proteins are more efficient in triggering GLP-1 than fats and carbohydrates
doi:10.1016/j.bbrc.2013.12.049 114
