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Animal experiments also suggest that liraglutide has a neuroprotective effect in murine models of Parkinson's disease (PD), which is accomplished by activating PGC-1 to regulate mitochondria biogenesis, dynamics, autophagy, and apoptosis in substantia nigrathe region in the brain that gets damaged by PD [22]

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Interestingly, L585 could only be replaced with an amino acid having similar physiochemical properties, including isoleucine, methionine, and valine, without negatively affecting FcRn binding 64

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