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Genetic deletion of monocaylglyceride-acyltransferase-2 (MGAT2) and diacylglyceride-acyltransferase-1 (DGAT1), enzymes involved in the stepwise re-esterification of MAGs to triacylglycerides (TAGs) inside intestinal epithelial cells, results in a reduced GIP-response to oral oil gavage [65]

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This weight loss is mainly attributed to decreased appetite and enhanced feelings of fullness, resulting in reduced calorie consumption