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With incretin-based drugs, much of the reported lean mass loss may not be skeletal muscle, but some is

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Conclusions We found no signal of disproportionate reporting of an association between GLP-1RA use and SSIBs

Tirzepatide was more efficacious in reducing body weight

Henney 2024) demonstrated a potentially meaningful reduction in incident pneumonia with GLP-1 RAs compared with dipeptidyl peptidase-4 (DPP-4) inhibitors (hazard ratio [HR] 0.60, 95% confidence interval [CI] 0.580.62
Joel Habener, Lotte Bjerre Knudsen, Svetlana Mojsov
