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University College Londons professor John Deanfield, who led the study, said the findings have important clinical implications and suggests semaglutide has another mechanism to lower cardiovascular risk other than reducing unhealthy body fat, adding that many more patients than are taking it now would likely benefit from the drug

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The REWIND trial was noteworthy as, from its total of 9,901 participants, the majority (68.5%) had CV risk factors only at baseline and fewer than one-third (31.5%) had established CVD

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