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Description
SURMOUNT-1 trial

10.1136/bmjopen-2022-061807 40

For someone with moderate risk, early metabolic dysfunction, family history, preserving cognition may tip the scale

Timper K, Grisouard J, Sauter NS et al (2013) Glucose-dependent insulinotropic polypeptide induces cytokine expression, lipolysis, and insulin resistance in human adipocytes

Higher adherence to plant-based diets are associated with lower likelihood of fatty liver

Thus, the search for non-peptide oral GLP-1 RAs to overcome absorption difficulty, and the progress of orforglipron without these administration restrictions, are very welcome
