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Results vary, as some patients put weight on and 17.7% of semaglutide users regained all, or more, of their initial starting weight

A notable RCT is the pioglitazone in early PD trial, which failed to demonstrate the possibility of pioglitazone delaying disease progression in early-stage PD patients [38]

Originally developed to treat type 2 diabetes, this GLP-1 receptor agonist is now approved and used for effective weight loss helping to regulate appetite, reduce cravings, and support long-term lifestyle change

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The study also found: Almost 8 in 10 people on the Wegovy pill lost at least 5 percent of their starting weight, compared with about 3 in 10 taking a placebo pill

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