glp-1 side effects cancer Your guide to GLP-1 drugs can cause pancreatitis,
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doi: 10.1016/j.mcna.2018.10.009 [DOI] [PubMed] [Google Scholar] 80

Li, D.-J

doi: 10.1016/j.gie.2021.07.021

Hollander, E

Diabetes Care, 48 (1 Suppl 1), S167S180

The review covered GLP-1s roles in controlling islet function, appetite, inflammation, and cardiovascular pathophysiology, and made a critical mechanistic distinction: native GLP-1 acts primarily via paracrine and neural mechanisms (given its 12 minute plasma half-life), whereas GLP-1RA drugs with extended half-lives act systemically on GLP-1R populations inaccessible to the native peptide