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Description
Semaglutide GLP-1 for weight loss is administered through a once-weekly subcutaneous injection

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This staged retatrutide dosing schedule reflects an approach common across the GLP-1 receptor agonist class, where initiating at the target dose significantly increases the frequency and severity of gastrointestinal adverse events
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doi: 10.1080/14656566.2020.1795132, PMID: [DOI] [PubMed] [Google Scholar] 85

For the last 50 years, bariatric surgery has been the most effective treatment for obesity resulting in approximately 25% weight loss, whilst also improving the control of type 2 diabetes mellitus (T2DM) and reducing cardiovascular and cancer deaths
