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GLP-1 receptor agonists are being studied for IBS symptom relief, with emerging research showing potential benefits for gut motility and visceral sensitivity

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GLP-1 stimulation induced serine phosphorylation of wild-type GLP-1R, which was abolished in all individual doublet as well as triple doublet phospho-null mutants

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In the US, cash-paying patients have a 12-month persistence rate of 13%, while insured individuals see rates of 36%4

Observed outcomes in study environments have included changes in biomarkers associated with metabolic function and body weight parameters
