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Description
The STEP (Semaglutide Treatment Effect in People with obesity) trials, which included over 4,500 participants, showed that semaglutide 2.4 mg weekly resulted in mean weight loss of 12.4% to 15.3% of initial body weight over 68 weeks, compared to 2.4% to 3.2% with placebo

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The starting dose is subtherapeutic for most people

And one area that has been a consideration over the last, well, frankly, going back many hundreds of years, but really came into sharper focus, I would say the last 10 to 20 years, is the possibility that theres something thats gone awry, somethings gone off the rail, so to speak, with the metabolism of the human brain

One trial examining semaglutide in individuals with AUD demonstrated lower alcohol intake, but reported inconsistent effects on heavy drinking days

Ramin, a tiny wire basket is passed into the ureter to pull out the stone
