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Under this model, legitimacy is presented as a sequence

Obesity increases inflammation and endothelial dysfunction and is associated with hypertension, dyslipidaemia, and glucose intolerance [84, 85]

Semaglutide and tirzepatide trials show meaningful average weight loss when used with lifestyle intervention, but the goal shouldn't be to lose as much scale weight as possible at any cost
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Overweight, obesity, and risk of cardiometabolic multimorbidity: pooled analysis of individual-level data for 120 813 adults from 16 cohort studies from the USA and Europe

Verrengia M, Sachdeva P, Gaughan J, et al
