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Evidence highlights ipamorelins favorable safety profile in short-term studies but underscores gaps in long-term data

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Federal law defines drug shortage as a period of time when the demand or projected demand for the drug in the United States exceeds the supply, 21 USC 356c(h)(2), and FDA considers a shortage resolved when all the manufacturers are able to meet total national historical demand. This is the statutory authority upon which compounded copies of FDA approved GLP-1 drugs have proliferated in the United States creating greater access at a lower cost for patients, albeit with a greater safety risk than the approved, brand named versions