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However, hunger feelings and AG concentrations increase significantly from baseline, once refeeding occurs.

Enteroendocrine L-cell derived peptide hormones, notably glucagon-like peptide-1 (GLP-1) and glucagon-like peptide-2 (GLP-2), have become important targets in the treatment of type 2 diabetes, obesity and intestinal diseases

Those numbers are particularly pronounced in states where the obesity rate is higher