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That worked out to a 20% reduction in clot risk, Patell and his colleagues noted

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Wang W, Mei A, Qian H, Li D, Xu H, Chen J, et al

In the central nervous system (CNS), GLP-1 and GLP-1R agonists are diffused into the cerebrospinal fluid (CSF) and the brain as demonstrated in rodent models (Wang et al., 2015), and increased GLP-1 concentration in the brain is thought to influence brain function in the hippocampus (Kastin et al., 2002

[DOI] [PubMed] [Google Scholar] Arans C., Edvardsson C.E., Shevchouk O.T., Zhang Q., Witley S., Blid Skldheden S., Zentveld L., Vallf D., Tufvesson-Alm M., Jerlhag E

Options for both companies may include semaglutide or tirzepatide, depending on clinical appropriateness, availability, and insurance coverage