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These include: Obesity : Excess body weight can increase the risk of kidney stones due to changes in the acid levels in urine
After initiating tirzepatide she lost 21 pounds in 13 days
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The Wegovy SmPC lists the following as occurring in more than 1 in 10 patients on the 2.4 mg dose [1] : nausea (44% on semaglutide vs 16% on placebo), diarrhoea (30% vs 16%), vomiting (24% vs 6%), constipation (24% vs 11%), and abdominal pain
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Orlistat, one of the most well-known PL inhibitors, offers a case study on the effectiveness, challenges, and side effects associated with this therapeutic approach [24]
