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Some health professionals say the drugs are highly effective at combating obesity, a chronic disease that drives up health care costs because it can lead to many other disorders such as heart disease and diabetes

Appetite control appears to be at the center of sustained weight loss with retatrutide

(Photo by Alexander Castro/Rhode Island Current) Rhode Islands Medicaid program is contemplating an end to coverage for GLP-1 drugs prescribed for weight loss

It is also estimated that 1.3 million people are currently living with type 2 diabetes but are yet to be diagnosed

The combination of GLP-1 receptor agonists and DPP-4 inhibitors is not recommended, not due to safety issues, but since a clinically significant additional benefit is not expected (see below) (7072)

Its given as a small injection under the skin and is designed for people who are overweight or have obesity