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Recent observations and emerging research have raised concerns about increased tendon injuries and declining bone health in some individuals using GLP-1 therapies

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These incidents became much more common after the FDA started approving GLP-1 drugs for chronic weight management in 2021.

A retrospective analysis of 105,000+ patients revealed: 40% lower OSA risk with tirzepatide (Zepbound) or semaglutide (Wegovy) vs non-AOM users Lower OSA incidence: 3.12% vs 12.56% Comparable impact between tirzepatide and semaglutide, with tirzepatide showing a slight edge after 6 months This study highlights the potential for AOMs to address obesity and OSA, supporting broader healthcare value through comorbidity reduction

The GLP-1 Strength Training Blueprint for Women Over 40: At-Home Workouts to Preserve Lean Muscle, Burn Fat, and Beat Menopausal Weight Gain on GLP-1 Medications - Kindle edition by Gomez, Marisol, Press, Diamond Door