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A large systemic review of cardiovascular outcomes of people taking GLP-1 agonists significantly reduces death from cardiovascular causes by 12% and stroke by 16%

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By binding to these receptors, GLP-1RAs induce calorie expenditure through mechanisms that mimic a fasting-mimicking metabolic state

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Am J Physiol Gastrointest Liver Physiol (2014) 306(4):G3019.10.1152/ajpgi.00383.2013 54 IshiiMNakamuraTKasaiFOnumaTBabaTTakebeK