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A particular capability of semaglutide is to exert anti-inflammatory effects, possibly by inhibiting the expression of key factors in WAT inflammation S100a8, S100a9 and Cxcl2 in neutrophils [110,111]

GIP (glucose-dependent insulinotropic polypeptide): Secreted in the small intestine, GIP works mainly in the pancreas to help regulate insulin release and blood sugar levels

Weaver, J

Hygum K, Harslf T, Jrgensen NR, Rungby J, Pedersen SB, Langdahl BL (2020) Bone resorption is unchanged by liraglutide in type 2 diabetes patients: a randomised controlled trial

Any consideration of its use in type 1 diabetes should be made with caution and under strict medical supervision

The main analysis of the primary endpoint was performed as an intention-to-treat analysis including all patients (full analysis set)