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[DOI] [PMC free article] [PubMed] [Google Scholar] 119.Zhang Y., Luo M., Jia Y., Gao T., Deng L., Gong T., Zhang Z., Cao X., Fu Y

The common side effects of GLP-1 analogues include constipation and gastrointestinal discomfort, which are usually temporary and manageable

25 Changing GIP Ile 17 to Ala massively lowered the insulinotropic effect

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[1] [3] Administered as a once-weekly subcutaneous injection, it works by mimicking the action of the naturally occurring hormone GLP-1, which stimulates insulin secretion in response to elevated blood glucose levels, suppresses glucagon release, and slows gastric emptying
