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HRT addresses the upstream hormonal withdrawal

Estimated Current GLP-1 Use Among American Women This estimate includes all reasons for use, not just weight loss

For GLP-1 analogs, meta-analyses have shown that women tend to experience greater weight loss than men, with a mean difference of approximately 1 kg, potentially due to sex-specific differences in GLP-1 receptor expression and hormonal interactions.[55] This more favorable response in women may also be attributable to interactions between estrogen and GLP-1, as demonstrated by preclinical studies in mice.[56,57] Regarding MSTN inhibition, sex-based variation has been reported in both circulating MSTN levels and physiological responses

lecture fees from Novo Nordisk, AstraZeneca, and MSD

For eligible patients, medical therapiesincluding GLP-1based medicationsmay be introduced as part of a comprehensive plan