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Description
Glucagon-like peptide-1 (GLP-1) receptor agonists were touted as breakthrough drugsin 2023 and their popularity has soared since. More than 4 million items of tirzepatide and semaglutide were dispensed on the NHS in England in 2025/20261, while around2.5 million people each monthaccessed GLP-1s privately at the end of 2025, according to James Kingsland, chair of []

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This Topic Guide brings together everything Peter has discussed across podcasts, AMAs, and writing to help you understand how GLP-1 agonists work, what the evidence actually shows, and how to reason clearly about their roleif anyin a sustainable, long-term approach to health.

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