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Vildagliptin: a review of its use in type 2 diabetes mellitus

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Afonso, G

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Knerr et al

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Specific metabolic changes observed during GLP-1 treatment include: Improved insulin sensitivity , allowing cells to use glucose more efficiently Reduced hepatic glucose production , contributing to better glycaemic control Changes in body composition , with loss of both fat mass and some lean tissue Alterations in lipid metabolism , often resulting in improved cholesterol profiles Body composition studies suggest that lean tissue loss typically accounts for approximately 20-30% of total weight lost during GLP-1 therapy, though this varies considerably between individuals and depends on concurrent physical activity and protein intake

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Clin Transl Gastroenterol 2024;15(11):e00772

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Ozempic does not directly change the smell of your urine, but it can cause indirect changes

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