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In parallel, the amount of intracellular lipids decreased in a dose-dependent manner, indicating a reduced pool available for sebum synthesis

Tabira, J
Effects of medium-chain triglycerides on weight loss and body composition: a meta-analysis of randomized controlled trials

It appears that the IL-6 secreted into the blood crosses the blood-brain barrier in endothelial cells, activates microglia, and starts a cascade of inflammatory effects that result in activation of inflammasomes, secretion of IL-1 beta, and other downstream neurobiological changes associated with depression
