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HassapidouM., VlassopoulosA., Kalliostra M

The difference is less than 0.2 mg, which is clinically insignificant

Given that potentially dangerous islet cell hyperplasia is reported to occur in some T2DM patients treated with GLP-1R agonists, 79 it might be possible to design allosteric modulators of the GLP-1R that preferentially stimulate insulin secretion rather than islet growth

PMID: 33011770 In this study, the researchers used data from The Health Improvement Network a large database of anonymised electronic medical records collected from 808 UK primary care clinics