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Purpose-built for physicians Human, exendin-based GLP-1 receptor agonists similarly reduce CV, renal risk in diabetes A pooled study assessing trials of eight GLP-1 receptor agonists showed all reduce risk for a combined endpoint of major adverse cardiovascular events, regardless of structural homology to human GLP-1, as well as individual CV components

Gill, A

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Methods This narrative review synthesizes current evidence regarding the pharmacology and gastrointestinal effects of GLP-1 receptor agonists and dual GIP/GLP-1 receptor agonists