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Treatment of HFpEF beyond the SGLT2-Is: Does the addition of GLP-1 RA improve cardiometabolic risk and outcomes in diabetic patients

The study design was based on the elevation of LCFAs and reduction of GLP-1 secretion in the colon of DIO mice 17

JAMA Network
There is no known cure or medication to treat the condition
According to a recently released approval letter, the FDA has instructed Eli Lilly to study potential risks associated with Foundayo, especially those related to the heart and liver

Individual factors and clinical context should guide any decisions