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Predefined sensitivity analyses to determine potential confounding influence were conducted with the same statistical analysis set-up removing (1) patients with IIH without papilledema (IIH-WOP), and (2) patients with pre-existing migraine

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Clinical Practice Research Datalink, we emulated a target trial through an active-comparator new-user cohort design, comparing GLP-1 receptor agonists to SGLT-2 inhibitors

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In rats, it may be activated by peripheral signals, such as distension of the stomach that activate the GLP-1expressing neurons of the NTS, 28 and it has also been associated with enteroceptive stress