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Semaglutide has been linked to inflammation of the pancreas (pancreatitis) and to gallbladder problems, although this is rare

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Parallel fibrogenesis in the liver and myocardium adds to ventricular stiffness and diastolic dysfunction, while gut dysbiosis from a Western diet heightens systemic inflammation and endotoxemia, worsening cardiac and hepatic dysfunction

2016;11(5) doi: 10.1371/journal.pone.0154727

May 27, 2026 Summary: A survey finds that 35% of adults who tried GLP-1 medications stopped taking them, most commonly due to reaching their target weight, experiencing side effects, or lacking affordable coverage each posing distinct challenges for employers designing benefits

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