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Clinical trials show average weight loss of 15-20% of body weight over 68 weeks with semaglutide (Wegovy) and 15-22% with tirzepatide (Zepbound)
doi: 10.1016/S0140-6736(21)01443-4 [DOI] [PubMed] [Google Scholar] 193.Del Prato S, Kahn SE, Pavo I, et al
Glucagon-like peptide-1 regulates the beta cell transcription factor, PDX-1, in insulinoma cells
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10.1210/me.2005-0187
Mainous AG, Yin L, Wu V et al
