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The Overlapping Biology of Addiction and Obesity Research shows SUDs share biological and psychological similarities with overeating and obesity, with both involving dysregulation of the brains reward system (Srinivasan et al., 2025)
These effects collectively improve blood sugar control in patients with type 2 diabetes

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People who get the most from metabolic supplements are those who have already addressed the fundamentals: adequate protein intake , sufficient fiber, regular exercise, consistent sleep, and stress management
In patients receiving GLP-1 RAs for diabetes, the most obvious harm from holding them is poorly controlled blood glucose

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