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Doing so contributes to the broader evidence base and helps improve safety monitoring for emerging treatments such as retatrutide

The weight-loss drug Wegovy lowered heart attack risk in a large trial Weekly injections of the medication cut the number of serious heart problems PHILADELPHIA At the recent American Heart Association meeting, a cavernous room full of doctors erupted into applause

Although the evidence is not clear, experts claim this effect could be due to GLP-1-induced functional changes in glucose metabolism and reduced appetite Lean muscle loss: Rapid weight loss requires a calorie deficitmeaning your calorie intake is lower than calories burned in a day

Still, you should not give the injections right next to each other

Check in with your care team if side effects feel impactful

Your results will depend on: Healthier eating Level of activity Weight at the start of treatment Metabolic rate Chosen diet Those with severe obesity (class II or class III) tend to shed weight much more easily and will see significant results in as little as a couple of weeks