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Subjects received once-weekly subcutaneously administered semaglutide or volume-matched placebo for 13 weeks, with 5 weeks follow-up (Fig

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Indeed, an emerging body of evidence reviewed below highlights a novel role for central GLP-1 receptor-expressing circuits in regulating the reinforcing efficacy of cocaine and the behavioral mechanisms underlying cocaine taking-and seeking-behaviors

Food and Drug Administration (FDA) has approved two oral GLP-1 options: Wegovy (semaglutide) and Foundayo (orforglipron)

Tirzepatide should never be used as monotherapy for depression its an adjunct to established antidepressant therapy, not a replacement