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Bone and Muscle Loss When people lose a substantial amount of weight in a short amount of time, they also lose some muscle

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Contributions of fasting and postprandial plasma glucose increments to the overall diurnal hyperglycemia of type 2 diabetic patients: variations with increasing levels of HbA(1c)
In the first trial, lixisenatide 20 g QD (n = 46) and liraglutide 1.2 (n = 44) and 1.8 mg QD (n = 46) were compared following 8 weeks treatment in 142 subjects with T2DM not adequately controlled with insulin glargine with or without metformin [17]

The warning states that healthcare providers and family members should monitor patients for any signs of worsening mood when starting an antidepressant

It is the correct clinical framing
