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First, appetite suppression reduces total food intake dramatically
Hanssen R, Rigoux L, Kuzmanovic B, Iglesias S, Kretschmer AC, Schlamann M, et al
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In contrast, long acting GLP-1 receptor agonists have relatively little effect on the rate of gastric emptying due to the development of tachyphylaxis resulting from continuous activation of the GLP-1 receptors in the GI tract (Nauck et al, 2011
I will be straightforward: I do not have a clear mechanistic explanation to offer here
[DOI] [PubMed] [Google Scholar] 555.Campbell JE, et al
