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Animal toxicology studies have shown that semaglutide can cause thyroid C-cell tumors in rodents in a dose- and duration-dependent manner

GLP-1 (glucagon-like peptide-1) receptor agonists, such as liraglutide, semaglutide, and dulaglutide, are medications commonly used to help manage T2D and aid in weight loss

Individual factors significantly affect actual results, so the best medication depends on individual circumstances and should be determined with healthcare providers

Insomnia and sleep disturbances are not listed among the common adverse reactions for tirzepatide in the FDA-approved prescribing information for either Mounjaro or Zepbound

Waist circumference measures abdominal fat distribution

Separate meta-analyses were performed for each major comparator class