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Beyond regulatory approval, meaningful weight-loss outcomes depend on individual metabolic health, behavioral adherence, and baseline metabolic markers

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In some trials for obesity or diabetes, participants have reported changes in mood or energy, but these findings are not specific to bipolar disorder

10.1001/jama.2017.14752 256

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Hepatic toll-like receptor 4 expression is associated with portal inflammation and fibrosis in patients with NAFLD
