glp 1 and vagus nerve Microbiota-gut-brain axis: relationships among the nerve, gut microbiota, obesity, diabetes GLP-1 programs the neurovascular landscape:

2023Tirzepatide after intensive lifestyle intervention in adults with overweight or obesity: the SURMOUNT-3 phase 3 trial

Cell-type-dependent dissolution of CuO nanoparticles and efflux of Cu ions following cellular internalization

FUTURE PERSPECTIVES Long-term outcomes While strong evidence supports the kidney-protective effects of both SGLT2 inhibitors and GLP-1 receptor agonists, the long-term durability of these benefits remains uncertain (Table 2)

(3) Organ-centric reductionism: the current investigations predominantly focus on isolated organ systems, neglecting BBRs pleiotropic effects within inter-organ communication networks critical to systemic metabolic regulation

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Further potential of GLP-1 RAs Osteoarthritis Osteoarthritis (OA) is a condition where the entire joint undergoes wear and tear, leading to the loss of cartilage, swelling in the joint lining, and thickening of the bone under the cartilage, which may cause the formation of bone spurs