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Real-world evidence on the utilization, clinical and comparative effectiveness, and adverse effects of newer GLP-1RA-based weight-loss therapies

For patients, it is smart to keep taking thyroid medication consistently, on schedule, and to report any new symptoms after starting GLP-1/GIP therapy

Toxicol Pathol 43: 1004-1014, 2015

GLP-1 receptor agonists (GLP-1RAs) are antidiabetic drugs that help control blood glucose levels and support weight loss in people with or without type 2 diabetes [3, 617]

The list price for Zepbound is about $1,000 a month, although people with insurance coverage for the drug will likely pay less

studies have observed that when treatment duration exceeds 20 weeks, and weight loss exceeds 5%, recovery of SHBG and resolution of functional hyperandrogenism are more pronounced and correlate with both baseline HOMA-IR and the magnitude of weight loss (125, 126)