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Since most ingested allulose is absorbed and excreted in urine, with only a fraction reaching the colon, the direct microbiome effects may be less significant than initially hypothesized

If you experience severe abdominal pain, persistent vomiting, signs of an allergic reaction, or anything that feels unusual, contact your primary care physician first , as they have your full medical history and can provide appropriate guidance

Interim data from the ESSENCE trial revealed that 62.7% of patients treated with semaglutide had improved steatohepatitis and 37% had improved liver fibrosis compared to 34.1% and 22.5%, respectively, who received placebo

Loading saturates faster (5 to 7 days) at roughly 0.3 g/kg/day for the loading window (about 20 to 25 g for a 70 to 80 kg adult), but is optional and produces no greater long-term benefit

As mentioned, GLP-1RAs can treat NAFLD through multiple mechanisms
