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"In order to adapt to this environment, we need all the tools we can find," Lembke said

Ongoing and future largescale randomized trials will be critical for clarifying efficacy and safety for this use

v21i1e298 [DOI] [PMC free article] [PubMed] [Google Scholar] 54.Jastreboff AM, Aronne LJ, Ahmad NN, Wharton S, Connery L, Alves B, Kiyosue A, Zhang S, Liu B, Bunck MC, Stefanski A, SURMOUNT-1 Investigators Tirzepatide once weekly for the treatment of obesity

It is the first oral GLP-1 medication approved specifically for weight management

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Poor sleep can disrupt hormones that regulate appetite (ghrelin and leptin), leading to increased hunger and cravings, and can hinder weight loss efforts